The neoprene is genuinely soft, no red marks or sore wrists after a long session, which surprised me. They still hold up fine when you pull, so you get comfort without them feeling flimsy. Easy to wipe clean too.
I was worried cuffs would dig in during longer sessions, but the neoprene padding stays soft the whole time. The material has enough give that I can tighten them without any pinching, and they wipe clean easily afterward.
The neoprene is surprisingly plush against the skin while still feeling totally secure when I pull the binding tight. I've used them a handful of times now and the material hasn't frayed or lost its grip, which is exactly what I want for something this versatile.